Search results for " fibers"
showing 10 items of 487 documents
Demonstration of polarization pulling in a fiber-optical parametric amplifier
2012
International audience; We report the experimental demonstration of all-optical polarization pulling of an initially polarization-scrambled signal using a fiber-optical parametric amplifier. Nonlinear polarization pulling has been achieved for both the signal and idler with 25 dB gain.
UV-Photoinduced Defects In Ge-Doped Optical Fibers
2005
We investigated the effect of continuous-wave (cw) UV laser radiation on single-mode Ge-doped H2- loaded optical fibers. An innovative technique was developed to measure the optical absorption (OA) induced in the samples by irradiation, and to study its dependence from laser fluence. The combined use of the electron spin resonance (ESR) technique allowed the structural identification of several radiation-induced point defects, among which the Ge(1) (GeO4 -) is found to be responsible of induced OA in the investigated spectral region.
Catecholamine release in human skin--a microdialysis study.
2003
Dermal microdialysis might be a promising tool to investigate properties of sympathetic neurons in the skin as investigation of peripheral noradrenergic neurons in humans usually relies on highly variable vasoconstrictor reflexes or on indirect measurements like skin temperature recordings. To evaluate this technique, 21 experiments were performed in 15 healthy subjects with four intracutaneous microdialysis fibers (diameter, 200 microm; cutoff, 5 kDa) at hands or feet. After 60 min, saline perfusion tyramine at concentrations of 0.195 to 200 microg/ml was applied for 15 min followed by a 15-min saline perfusion again. Catecholamine concentrations were detected through high-performance liqu…
Biallelic mutations in neurofascin cause neurodevelopmental impairment and peripheral demyelination
2019
See Karakaya and Wirth (doi:10.1093/brain/awz273) for a scientific commentary on this article. Neurofascin (NFASC) isoforms are immunoglobulin cell adhesion molecules involved in node of Ranvier assembly. Efthymiou et al. identify biallelic NFASC variants in ten unrelated patients with a neurodevelopmental disorder characterized by variable degrees of central and peripheral involvement. Abnormal expression of Nfasc155 is accompanied by severe loss of myelinated fibres.
Frequency comb generation by electro-optic modulation and applications
2020
The work presented in this thesis relates the development of a dual frequency comb spectrometer based on the electro-optic modulation of a continuous wave laser, and its utilisation for spectroscopic applications in the near- and mid-infrared.Since their discovery in the 1960s, frequency combs have revolutionised the physics, especially in metrology but also in spectroscopy, which lead to the Nobel Prize in Physics in 2005. In this domain of applications, dual frequency comb spectrometers are known to be complex to develop and use. A possibility to bypass these constraints is to build the spectrometer with electro-optic modulators. This particular architecture makes the experimental setup e…
A New System for Choosing the Form and Size of Complete Denture Anterior Teeth
2016
Introduction: In the absence of pre-extraction records, the choice of the size an form of anterior complete denture teeth can be extremely subjective. Several clinical and statistical parameters are usually used for choosing the correct size and form of the complete denture anterior teeth. Clinical Innovation: The technique consists of a system that allows the dentist to choose and, if necessary, easily change the dental mold during maxillomandibular recording session. The unique feature of the system is that six teeth of each mold are represented by veneers, which are connected to each other on the lingual surface by a fiber that allows each veneer some degree of movement. Discussion: This…
Spinal Endocannabinoids and CB 1 Receptors Mediate C-Fiber–Induced Heterosynaptic Pain Sensitization
2009
Plastic Pain Perception Drugs and endocannabinoids acting on cannabinoid (CB) receptors have potential in the treatment of certain types of pain. In the spinal cord they are believed to suppress nociception, the perception of pain and noxious stimuli. Pernia-Andrade et al. (p. 760 ) now find that endocannabinoids, which are released in spinal cord by noxious stimulation, may promote rather than inhibit nociception by acting on CB1 receptors. Endocannabinoids not only depress transmission at excitatory synapses in the spinal cord, but also block the release of inhibitory neurotransmitters, thereby facilitating nociception.
Automatic estimation of Purkinje-Myocardial junction hot-spots from noisy endocardial samples: A simulation study
2017
The reconstruction of the ventricular cardiac conduction system (CCS) from patient-specific data is a challenging problem. High-resolution imaging techniques have allowed only the segmentation of proximal sections of the CCS from images acquired ex vivo. In this paper, we present an algorithm to estimate the location of a set of Purkinje-myocardial junctions (PMJs) from electro-anatomical maps, as those acquired during radio-frequency ablation procedures. The method requires a mesh representing the myocardium with local activation time measurements on a subset of nodes. We calculate the backwards propagation of the electrical signal from the measurement points to all the points in the mesh …
Numerical study of an optical regenerator exploiting self-phase modulation and spectral offset filtering at 40 Gbit/s
2008
Topic: Nonlinear optics; International audience; In this work, we numerically investigate the performances of optical regenerators based on self-phase modulation and spectral offset filtering at 40 Gbit/s. We outline the different effects affecting the device performances and explain the choice of the optimal working power. The impact of the regenerator on the output signal is also analysed through a statistical approach. Both single- and double-stage configurations are investigated.
Therapeutic targets for overactive bladder other than smooth muscle
2015
For a long time, our concepts of regulation of urinary bladder function in health and disease as well as of the target structures of therapeutics have focused on detrusor smooth muscle cells. However, other structures including urothelium, afferent nerves and bladder blood vessels may also be important in pathophysiology and its treatment.Based on a selective review of literature, we discuss the role of urothelium, afferent nerve fibers and bladder blood vessels in bladder pathophysiology and as targets for treatment.There is solid evidence now that multiple anatomical structures within the urinary bladder contribute to the regulation of its function and hence may be targets for established…